KPV - KEGG Pathway Viewer

Term	Meaning
Metabolic pathway	In biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell. The term network is sometimes defined to mean a graph in which attributes (e.g. names) are associated with the vertices and edges, and the subject that expresses and understands the real-world systems as a network is called network science.
Network/Graphs	In mathematics, graph theory is the study of graphs, which are mathematical structures used to model pairwise relations between objects.
Network visualization	Graph visualization is a way of representing structural information as diagrams of abstract graphs and networks. It has important applications in networking, bioinformatics, software engineering, database and web design, machine learning, and in visual interfaces for other technical domains.
Node	In mathematics, and more specifically in graph theory, a vertex (plural vertices) or node is the fundamental unit of which graphs are formed.
Edge	For an undirected graph, an unordered pair of nodes that specify a line joining these two nodes are said to form an edge. For a directed graph, the edge is an ordered pair of nodes. The terms "arc," "branch," "line," "link," and "1-simplex" are sometimes used instead of edge.
KEGG	KEGG: Kyoto Encyclopedia of Genes and Genomes is a Japanese database resource for understanding high-level functions and utilities of the biological system, such as the cell, the organism and the ecosystem, from molecular-level information, especially large-scale molecular datasets generated by genome sequencing and other high-throughput experimental technologies.
KEGG Pathway	KEGG PATHWAY is a collection of manually drawn pathway maps representing the knowledge on the molecular interaction, reaction and relation.
Pathway code	Each pathway map is identified by the combination of 2-4 letter prefix code and 5 digit number.
Articulation point	In a graph, a vertex is called an articulation point if removing it and all the edges associated with it results in the increase of the number of connected components in the graph.
Articulation point impact	The impact is defined as the number of vertices that get disconnected from the main (largest) surviving connected component after the removal of the articulation point node.
AP node	AP is the abbreviation for Articulation point.
HAP node	AP is the abbreviation for Hub and Articulation point.
HUB node	In network science, a hub is a node with a number of links that greatly exceeds the average.
Other nodes	In the context of this tool, other nodes represent nodes without classification.

Nodes	Edges
18	33

Articulation point with highest impact	Disconnected nodes when remove it
ec:1.8.1.3	14

Global metrics
4	3.6667	0.0313

Nodes classification
6	4	4	12

Total organisms
5351

Eukaryotes	Prokaryotes
498	4853

Animals	Plants	Fungi	Protists	Bacteria	Archaea
248	104	123	23	4727	126

list(REFERENCE = "PMID:12471498", AUTHORS = "Cook AM, Denger K.", TITLE = "Dissimilation of the C2 sulfonates.", JOURNAL = c("Arch Microbiol 179:1-6 (2002)", "DOI:10.1007/s00203-002-0497-0")), list(REFERENCE = "PMID:11082195", AUTHORS = "Laue H, Cook AM.", TITLE = "Biochemical and molecular characterization of taurine:pyruvate aminotransferase from the anaerobe Bilophila wadsworthia.", JOURNAL = c("Eur J Biochem 267:6841-8 (2000)", "DOI:10.1046/j.1432-1033.2000.01782.x")), list(REFERENCE = "PMID:12358600", AUTHORS = "Ruff J, Denger K, Cook AM.", TITLE = "Sulphoacetaldehyde acetyltransferase yields acetyl phosphate: purification from Alcaligenes defragrans and gene clusters in taurine degradation.", JOURNAL = c("Biochem J 369:275-85 (2003)", "DOI:10.1042/BJ20021455")), list(REFERENCE = "PMID:15073291", AUTHORS = "Bruggemann C, Denger K, Cook AM, Ruff J.", TITLE = "Enzymes and genes of taurine and isethionate dissimilation in Paracoccus denitrificans.", JOURNAL = c("Microbiology 150:805-16 (2004)", "DOI:10.1099/mic.0.26795-0")), list(REFERENCE = "PMID:15340795", AUTHORS = "Denger K, Weinitschke S, Hollemeyer K, Cook AM.", TITLE = "Sulfoacetate generated by Rhodopseudomonas palustris from taurine.", JOURNAL = c("Arch Microbiol 182:254-8 (2004)", "DOI:10.1007/s00203-004-0678-0")), list(REFERENCE = "PMID:15184572", AUTHORS = "Denger K, Ruff J, Schleheck D, Cook AM.", TITLE = "Rhodococcus opacus expresses the xsc gene to utilize taurine as a carbon source or as a nitrogen source but not as a sulfur source.", JOURNAL = c("Microbiology 150:1859-67 (2004)", "DOI:10.1099/mic.0.27077-0")), list(REFERENCE = "PMID:15883781", AUTHORS = "Styp von Rekowski K, Denger K, Cook AM.", TITLE = "Isethionate as a product from taurine during nitrogen-limited growth of Klebsiella oxytoca TauN1.", JOURNAL = c("Arch Microbiol 183:325-30 (2005)", "DOI:10.1007/s00203-005-0776-7")), list(REFERENCE = "PMID:4297098", AUTHORS = "Jacobsen JG, Smith LH", TITLE = "Biochemistry and physiology of taurine and taurine derivatives.", JOURNAL = c("Physiol Rev 48:424-511 (1968)", "DOI:10.1152/physrev.1968.48.2.424"))

KPV - KEGG Pathway Viewer
by Igor Brandão

Loading..

00430 Taurine and hypotaurine metabolism
Metabolism; Metabolism of other amino acids

18
NODES

33
EDGES

5351
ORGANISMS

4
COMMUNITIES

3.6667
AVG. DEGREE

0.0313
AVG. BETWEENNESS

6
ARTICULATION POINTS

12
OTHER NODES

Filters

Pathway Viewer

18

33

ec:1.8.1.3

14

4

3.6667

0.0313

6

4

4

12

5351

498

4853

248

104

123

23

4727

126

Global metrics
Communities	Avg. degree	Avg. betweenness
4	3.6667	0.0313

KPV - KEGG Pathway Viewer by Igor Brandão

Loading..

00430 Taurine and hypotaurine metabolism Metabolism; Metabolism of other amino acids

18 NODES

33 EDGES

5351 ORGANISMS

4 COMMUNITIES

3.6667 AVG. DEGREE

0.0313 AVG. BETWEENNESS

6 ARTICULATION POINTS

12 OTHER NODES