KPV - KEGG Pathway Viewer
by Igor Brandão

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Top 10 Biggest Pathways

Nodes Edges
00520 Amino sugar and nucleotide sugar metabolism 116 275
00230 Purine metabolism 115 370
00860 Porphyrin and chlorophyll metabolism 115 162
00140 Steroid hormone biosynthesis 107 184
00240 Pyrimidine metabolism 89 286
00904 Diterpenoid biosynthesis 89 88
00906 Carotenoid biosynthesis 89 105
00330 Arginine and proline metabolism 85 217
00270 Cysteine and methionine metabolism 79 222
00950 Isoquinoline alkaloid biosynthesis 77 90

Note: in metabolic pathways nodes represent metabolites and edges are reactions that are catalyzed by specific gene products.

Top 10 Pathways with most Articulation Points (AP)

Code Name Total AP (A + B)
00904 Diterpenoid biosynthesis 56 42 14 17 47
00906 Carotenoid biosynthesis 55 42 13 18 47
00520 Amino sugar and nucleotide sugar metabolism 51 41 10 23 75
00860 Porphyrin and chlorophyll metabolism 44 37 7 23 78
00941 Flavonoid biosynthesis 42 28 14 15 48
00100 Steroid biosynthesis 41 35 6 10 17
00380 Tryptophan metabolism 39 29 10 12 33
00140 Steroid hormone biosynthesis 32 28 4 21 79
00902 Monoterpenoid biosynthesis 31 25 6 9 22
00950 Isoquinoline alkaloid biosynthesis 31 27 4 15 50

Note:

AP Node classified as Articulation Point
HAP Node highly connected and Articulation Point
HUB Node highly connected
Others Node without classification

Top 10 Articulation Points impact

00230 Purine metabolism ec:2.1.3.5 107
00140 Steroid hormone biosynthesis ec:1.3.1.22_1 98
00240 Pyrimidine metabolism ec:4.1.1.23 83
00330 Arginine and proline metabolism ec:4.1.1.19, ec:1.5.1.1+_1, ec:2.6.1.1+_2 82
00520 Amino sugar and nucleotide sugar metabolism ec:5.3.1.9 77
00500 Starch and sucrose metabolism ec:2.4.1.10 72
00630 Glyoxylate and dicarboxylate metabolism ec:4.1.3.24_1 65
00564 Glycerophospholipid metabolism ec:2.5.1.42 64
00051 Fructose and mannose metabolism ec:3.1.1.65 57
00362 Benzoate degradation ec:4.1.3.39 57

Note: the articulation point (AP) impact refers to the number of nodes that are disconnected when the AP is removed.

Top 10 Pathways with most associated organisms

00970 Aminoacyl-tRNA biosynthesis 6112 531 5581 248 105 128 50 5282 299
00620 Pyruvate metabolism 6101 531 5570 248 105 128 50 5272 298
00010 Glycolysis / Gluconeogenesis 6097 531 5566 248 105 128 50 5269 297
00260 Glycine, serine and threonine metabolism 6086 530 5556 248 105 127 50 5259 297
00270 Cysteine and methionine metabolism 6084 527 5557 248 105 124 50 5261 296
00230 Purine metabolism 6083 531 5552 248 105 128 50 5253 299
00240 Pyrimidine metabolism 6083 531 5552 248 105 128 50 5253 299
00030 Pentose phosphate pathway 6064 531 5533 248 105 128 50 5236 297
00640 Propanoate metabolism 6063 530 5533 248 105 128 49 5236 297
00730 Thiamine metabolism 6055 530 5525 248 105 127 50 5229 296