KPV - KEGG Pathway Viewer

Term	Meaning
Metabolic pathway	In biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell. The term network is sometimes defined to mean a graph in which attributes (e.g. names) are associated with the vertices and edges, and the subject that expresses and understands the real-world systems as a network is called network science.
Network/Graphs	In mathematics, graph theory is the study of graphs, which are mathematical structures used to model pairwise relations between objects.
Network visualization	Graph visualization is a way of representing structural information as diagrams of abstract graphs and networks. It has important applications in networking, bioinformatics, software engineering, database and web design, machine learning, and in visual interfaces for other technical domains.
Node	In mathematics, and more specifically in graph theory, a vertex (plural vertices) or node is the fundamental unit of which graphs are formed.
Edge	For an undirected graph, an unordered pair of nodes that specify a line joining these two nodes are said to form an edge. For a directed graph, the edge is an ordered pair of nodes. The terms "arc," "branch," "line," "link," and "1-simplex" are sometimes used instead of edge.
KEGG	KEGG: Kyoto Encyclopedia of Genes and Genomes is a Japanese database resource for understanding high-level functions and utilities of the biological system, such as the cell, the organism and the ecosystem, from molecular-level information, especially large-scale molecular datasets generated by genome sequencing and other high-throughput experimental technologies.
KEGG Pathway	KEGG PATHWAY is a collection of manually drawn pathway maps representing the knowledge on the molecular interaction, reaction and relation.
Pathway code	Each pathway map is identified by the combination of 2-4 letter prefix code and 5 digit number.
Articulation point	In a graph, a vertex is called an articulation point if removing it and all the edges associated with it results in the increase of the number of connected components in the graph.
Articulation point impact	The impact is defined as the number of vertices that get disconnected from the main (largest) surviving connected component after the removal of the articulation point node.
AP node	AP is the abbreviation for Articulation point.
HAP node	AP is the abbreviation for Hub and Articulation point.
HUB node	In network science, a hub is a node with a number of links that greatly exceeds the average.
Other nodes	In the context of this tool, other nodes represent nodes without classification.

Nodes	Edges
68	154

Articulation point with highest impact	Disconnected nodes when remove it
ec:2.5.1.42	64

Global metrics
9	4.5294	0.0548

Nodes classification
7	2	14	61

Total organisms
6043

Eukaryotes	Prokaryotes
531	5512

Animals	Plants	Fungi	Protists	Bacteria	Archaea
248	105	128	50	5215	297

list(REFERENCE = "PMID:1512203", AUTHORS = "Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.", TITLE = "The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.", JOURNAL = c("J Bacteriol 174:5702-10 (1992)", "DOI:10.1128/JB.174.17.5702-5710.1992")), list(REFERENCE = "PMID:10092508", AUTHORS = "Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.", TITLE = "Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.", JOURNAL = c("Biochem Biophys Res Commun 257:50-6 (1999)", "DOI:10.1006/bbrc.1999.0411")), list(REFERENCE = "PMID:10542045", AUTHORS = "Athenstaedt K, Daum G.", TITLE = "Phosphatidic acid, a key intermediate in lipid metabolism.", JOURNAL = c("Eur J Biochem 266:1-16 (1999)", "DOI:10.1046/j.1432-1327.1999.00822.x")), list(REFERENCE = "PMID:12431977", AUTHORS = "Shields DJ, Lehner R, Agellon LB, Vance DE.", TITLE = "Membrane topography of human phosphatidylethanolamine N-methyltransferase.", JOURNAL = c("J Biol Chem 278:2956-62 (2003)", "DOI:10.1074/jbc.M210904200")), list(REFERENCE = "PMID:14663079", AUTHORS = "Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.", TITLE = "Pathways for phosphatidylcholine biosynthesis in bacteria.", JOURNAL = c("Microbiology 149:3461-71 (2003)", "DOI:10.1099/mic.0.26522-0")), list(REFERENCE = "PMID:15522832", AUTHORS = "Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.", TITLE = "Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.", JOURNAL = c("Biochim Biophys Acta 1686:161-8 (2004)", "DOI:10.1016/j.bbalip.2004.09.007")), list(REFERENCE = "PMID:1649829", AUTHORS = "Hsu L, Jackowski S, Rock CO", TITLE = "Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.", JOURNAL = "J Biol Chem 266:13783-8 (1991)"), list(REFERENCE = "PMID:10938271", AUTHORS = "Stone SJ, Vance JE.", TITLE = "Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.", JOURNAL = c("J Biol Chem 275:34534-40 (2000)", "DOI:10.1074/jbc.M002865200"))

KPV - KEGG Pathway Viewer
by Igor Brandão

Loading..

00564 Glycerophospholipid metabolism
Metabolism; Lipid metabolism

68
NODES

154
EDGES

6043
ORGANISMS

9
COMMUNITIES

4.5294
AVG. DEGREE

0.0548
AVG. BETWEENNESS

7
ARTICULATION POINTS

61
OTHER NODES

Filters

Pathway Viewer

68

154

ec:2.5.1.42

64

9

4.5294

0.0548

7

2

14

61

6043

531

5512

248

105

128

50

5215

297

Global metrics
Communities	Avg. degree	Avg. betweenness
9	4.5294	0.0548

KPV - KEGG Pathway Viewer by Igor Brandão

Loading..

00564 Glycerophospholipid metabolism Metabolism; Lipid metabolism

68 NODES

154 EDGES

6043 ORGANISMS

9 COMMUNITIES

4.5294 AVG. DEGREE

0.0548 AVG. BETWEENNESS

7 ARTICULATION POINTS

61 OTHER NODES